Dr. Louis-Marie Bobay, an assistant professor in the Department of Biology, has received more than $250,000 in continuation funding from the National Institutes of Health’s National Institute of General Medical Sciences for the project, “Investigating the impact and patterns of homologous recombination and adaptive evolution on bacterial genomes.”
This award is part of a larger, five-year, $1.5 M grant awarded in 2020.
Learn more about Dr. Bobay’s research here.
Project abstract:
Homologous recombination is a key mechanism driving bacterial adaptation to new environments and new treatments. The proposed study aims to apply a new approach to determine the rates and patterns of recombination across genomic and metagenomic data in order to identify the factors shaping the rates and landscapes of recombination as well as the impact of recombination on bacterial evolution and genome architecture. Upon completion, this project will provide a global view of the recombination process and its role in the adaptation and genomic organization of hundreds of bacterial species.
